high endothelial venule

high endothelial venule
Venules in which the endothelial cells are cuboidal rather than squamous. Found particularly in lymph nodes where there is considerable extravasation of lymphocytes as part of normal traffic. Morphologically similar endothelium is found associated with some chronic inflammatory lesions. Express particular adhesion molecules accounting for preferential lymphocyte adhesion.

Dictionary of molecular biology. 2004.

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